Physical Properties | | | |
Molecular Weight: 366.417 g/mol | logS: -3.48581 | SlogP: 1.7919 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.206288 | Sterimol/B1: 2.57788 | Sterimol/B2: 3.50759 | Sterimol/B3: 5.49047 |
Sterimol/B4: 8.10628 | Sterimol/L: 14.0213 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 586.193 | Positive charged surface: 414.445 | Negative charged surface: 171.748 | Volume: 350.25 |
Hydrophobic surface: 450.013 | Hydrophilic surface: 136.18 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |