Physical Properties | | | |
Molecular Weight: 410.537 g/mol | logS: -4.19085 | SlogP: 3.876 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.120345 | Sterimol/B1: 2.53464 | Sterimol/B2: 3.02408 | Sterimol/B3: 5.50796 |
Sterimol/B4: 11.8938 | Sterimol/L: 15.2565 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 690.332 | Positive charged surface: 491.711 | Negative charged surface: 198.621 | Volume: 406.5 |
Hydrophobic surface: 626.82 | Hydrophilic surface: 63.512 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |