Physical Properties | | | |
Molecular Weight: 403.455 g/mol | logS: -3.96963 | SlogP: 1.7612 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.254716 | Sterimol/B1: 3.17826 | Sterimol/B2: 3.9581 | Sterimol/B3: 5.54998 |
Sterimol/B4: 7.86398 | Sterimol/L: 14.8868 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 611.439 | Positive charged surface: 364.333 | Negative charged surface: 247.106 | Volume: 356.375 |
Hydrophobic surface: 508.767 | Hydrophilic surface: 102.672 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |