Physical Properties | | | |
Molecular Weight: 400.862 g/mol | logS: -4.50784 | SlogP: 4.3767 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0656997 | Sterimol/B1: 4.01478 | Sterimol/B2: 4.12815 | Sterimol/B3: 4.53398 |
Sterimol/B4: 9.56108 | Sterimol/L: 18.6394 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 690.626 | Positive charged surface: 411.284 | Negative charged surface: 279.342 | Volume: 370.625 |
Hydrophobic surface: 548.757 | Hydrophilic surface: 141.869 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |