Physical Properties | | | |
Molecular Weight: 424.516 g/mol | logS: -5.33268 | SlogP: 4.2972 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.174831 | Sterimol/B1: 2.28258 | Sterimol/B2: 4.51206 | Sterimol/B3: 5.76489 |
Sterimol/B4: 8.75352 | Sterimol/L: 16.2749 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 659.753 | Positive charged surface: 475.889 | Negative charged surface: 183.863 | Volume: 410.125 |
Hydrophobic surface: 614.098 | Hydrophilic surface: 45.655 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |