Physical Properties | | | |
Molecular Weight: 403.526 g/mol | logS: -5.40392 | SlogP: 5.11339 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0164939 | Sterimol/B1: 2.32626 | Sterimol/B2: 2.8972 | Sterimol/B3: 3.53364 |
Sterimol/B4: 7.39389 | Sterimol/L: 24.61 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 727.428 | Positive charged surface: 526.322 | Negative charged surface: 196.436 | Volume: 409.125 |
Hydrophobic surface: 650.121 | Hydrophilic surface: 77.307 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |