Physical Properties | | | |
Molecular Weight: 406.442 g/mol | logS: -2.92675 | SlogP: 3.0413 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0866435 | Sterimol/B1: 2.89843 | Sterimol/B2: 5.20101 | Sterimol/B3: 5.8495 |
Sterimol/B4: 9.07891 | Sterimol/L: 17.3243 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 680.195 | Positive charged surface: 503.148 | Negative charged surface: 177.047 | Volume: 381.75 |
Hydrophobic surface: 580.57 | Hydrophilic surface: 99.625 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |