Physical Properties | | | |
Molecular Weight: 425.572 g/mol | logS: -6.71491 | SlogP: 5.3769 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.02423 | Sterimol/B1: 2.9242 | Sterimol/B2: 3.48614 | Sterimol/B3: 4.49988 |
Sterimol/B4: 8.23144 | Sterimol/L: 23.564 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 758.118 | Positive charged surface: 492.96 | Negative charged surface: 259.392 | Volume: 418.75 |
Hydrophobic surface: 648.731 | Hydrophilic surface: 109.387 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |