Physical Properties | | | |
Molecular Weight: 404.506 g/mol | logS: -5.82192 | SlogP: 3.88717 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0502082 | Sterimol/B1: 3.75184 | Sterimol/B2: 3.8648 | Sterimol/B3: 4.56188 |
Sterimol/B4: 8.14533 | Sterimol/L: 17.8255 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 679.17 | Positive charged surface: 425.434 | Negative charged surface: 253.737 | Volume: 375.25 |
Hydrophobic surface: 563.247 | Hydrophilic surface: 115.923 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |