Physical Properties | | | |
Molecular Weight: 451.616 g/mol | logS: -3.43095 | SlogP: 0.7342 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0229498 | Sterimol/B1: 2.44163 | Sterimol/B2: 3.88973 | Sterimol/B3: 3.93201 |
Sterimol/B4: 5.84218 | Sterimol/L: 25.1904 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 754.121 | Positive charged surface: 528.823 | Negative charged surface: 225.298 | Volume: 412.375 |
Hydrophobic surface: 555.292 | Hydrophilic surface: 198.829 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |