Physical Properties | | | |
Molecular Weight: 422.53 g/mol | logS: -3.76599 | SlogP: 0.7044 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0659938 | Sterimol/B1: 2.53312 | Sterimol/B2: 2.5462 | Sterimol/B3: 5.28162 |
Sterimol/B4: 7.17051 | Sterimol/L: 18.1888 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 649.568 | Positive charged surface: 396.01 | Negative charged surface: 253.558 | Volume: 357.125 |
Hydrophobic surface: 367.782 | Hydrophilic surface: 281.786 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |