Physical Properties | | | |
Molecular Weight: 444.575 g/mol | logS: -7.09597 | SlogP: 6.08202 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0730366 | Sterimol/B1: 2.70173 | Sterimol/B2: 3.25307 | Sterimol/B3: 6.01737 |
Sterimol/B4: 10.2671 | Sterimol/L: 20.9658 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 772.209 | Positive charged surface: 508.769 | Negative charged surface: 263.44 | Volume: 453.375 |
Hydrophobic surface: 675.036 | Hydrophilic surface: 97.173 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |