Physical Properties | | | |
Molecular Weight: 416.434 g/mol | logS: -5.43597 | SlogP: 0.6458 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.165229 | Sterimol/B1: 3.30649 | Sterimol/B2: 5.20991 | Sterimol/B3: 5.77944 |
Sterimol/B4: 8.33381 | Sterimol/L: 13.4551 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 607.711 | Positive charged surface: 320.073 | Negative charged surface: 287.638 | Volume: 358.75 |
Hydrophobic surface: 291.021 | Hydrophilic surface: 316.69 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |