Physical Properties | | | |
Molecular Weight: 461.583 g/mol | logS: -5.02154 | SlogP: 3.1085 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.120168 | Sterimol/B1: 4.26387 | Sterimol/B2: 5.25122 | Sterimol/B3: 6.20035 |
Sterimol/B4: 8.19184 | Sterimol/L: 17.3825 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 742.527 | Positive charged surface: 521.108 | Negative charged surface: 221.419 | Volume: 432.5 |
Hydrophobic surface: 560.289 | Hydrophilic surface: 182.238 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |