Physical Properties | | | |
Molecular Weight: 399.342 g/mol | logS: -5.23816 | SlogP: 4.695 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.17907 | Sterimol/B1: 3.25469 | Sterimol/B2: 4.10548 | Sterimol/B3: 4.72055 |
Sterimol/B4: 9.03052 | Sterimol/L: 12.9894 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 596.931 | Positive charged surface: 271.242 | Negative charged surface: 325.689 | Volume: 347.625 |
Hydrophobic surface: 530.012 | Hydrophilic surface: 66.919 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |