Physical Properties | | | |
Molecular Weight: 396.471 g/mol | logS: -5.37009 | SlogP: 3.07541 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0650117 | Sterimol/B1: 3.50969 | Sterimol/B2: 4.7609 | Sterimol/B3: 4.89083 |
Sterimol/B4: 4.93084 | Sterimol/L: 20.54 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 670.789 | Positive charged surface: 405.539 | Negative charged surface: 265.25 | Volume: 360.375 |
Hydrophobic surface: 526.614 | Hydrophilic surface: 144.175 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |