Physical Properties | | | |
Molecular Weight: 376.463 g/mol | logS: -8.36445 | SlogP: 6.13952 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0431429 | Sterimol/B1: 3.1794 | Sterimol/B2: 3.23842 | Sterimol/B3: 4.7621 |
Sterimol/B4: 7.59986 | Sterimol/L: 18.041 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 658.564 | Positive charged surface: 391.303 | Negative charged surface: 262.325 | Volume: 379.25 |
Hydrophobic surface: 599.703 | Hydrophilic surface: 58.861 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |