Physical Properties | | | |
Molecular Weight: 404.945 g/mol | logS: -7.98987 | SlogP: 6.3673 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.210098 | Sterimol/B1: 2.41259 | Sterimol/B2: 2.50707 | Sterimol/B3: 7.17349 |
Sterimol/B4: 9.73514 | Sterimol/L: 16.0614 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 677.81 | Positive charged surface: 406.867 | Negative charged surface: 269.268 | Volume: 404.75 |
Hydrophobic surface: 574.943 | Hydrophilic surface: 102.867 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |