Physical Properties | | | |
Molecular Weight: 420.516 g/mol | logS: -8.74204 | SlogP: 6.53822 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0328037 | Sterimol/B1: 2.50983 | Sterimol/B2: 3.08703 | Sterimol/B3: 3.51338 |
Sterimol/B4: 10.3476 | Sterimol/L: 20.9588 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 739.636 | Positive charged surface: 465.06 | Negative charged surface: 269.458 | Volume: 421.625 |
Hydrophobic surface: 651.877 | Hydrophilic surface: 87.759 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |