Physical Properties | | | |
Molecular Weight: 372.441 g/mol | logS: -6.84154 | SlogP: 3.7265 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0935859 | Sterimol/B1: 4.15151 | Sterimol/B2: 4.49917 | Sterimol/B3: 4.74344 |
Sterimol/B4: 5.86274 | Sterimol/L: 16.8513 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 606.142 | Positive charged surface: 358.572 | Negative charged surface: 247.57 | Volume: 337.375 |
Hydrophobic surface: 442.817 | Hydrophilic surface: 163.325 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |