Physical Properties | | | |
Molecular Weight: 387.483 g/mol | logS: -4.66974 | SlogP: 4.2327 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.255735 | Sterimol/B1: 3.54675 | Sterimol/B2: 3.86753 | Sterimol/B3: 5.30945 |
Sterimol/B4: 7.94072 | Sterimol/L: 13.1806 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 578.674 | Positive charged surface: 382.691 | Negative charged surface: 192.892 | Volume: 376.875 |
Hydrophobic surface: 488.133 | Hydrophilic surface: 90.541 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |