Physical Properties | | | |
Molecular Weight: 445.587 g/mol | logS: -4.23548 | SlogP: 2.7285 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.104196 | Sterimol/B1: 3.40191 | Sterimol/B2: 6.48874 | Sterimol/B3: 6.53553 |
Sterimol/B4: 6.89301 | Sterimol/L: 19.9591 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 770.316 | Positive charged surface: 569.964 | Negative charged surface: 197.272 | Volume: 455.5 |
Hydrophobic surface: 681.59 | Hydrophilic surface: 88.726 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |