Physical Properties | | | |
Molecular Weight: 385.855 g/mol | logS: -6.98553 | SlogP: 4.8096 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0141834 | Sterimol/B1: 2.05372 | Sterimol/B2: 2.85047 | Sterimol/B3: 3.24633 |
Sterimol/B4: 9.72821 | Sterimol/L: 16.7535 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 675.825 | Positive charged surface: 419.275 | Negative charged surface: 256.55 | Volume: 356.25 |
Hydrophobic surface: 531.504 | Hydrophilic surface: 144.321 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |