Physical Properties | | | |
Molecular Weight: 477.523 g/mol | logS: -7.44069 | SlogP: 7.2519 | Reactive groups: 1 |
| | | |
Topological Properties | | | |
Globularity: 0.0997067 | Sterimol/B1: 2.21046 | Sterimol/B2: 2.39908 | Sterimol/B3: 6.12229 |
Sterimol/B4: 7.75376 | Sterimol/L: 19.0906 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 720.753 | Positive charged surface: 448.596 | Negative charged surface: 272.157 | Volume: 443.25 |
Hydrophobic surface: 495.657 | Hydrophilic surface: 225.096 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |