Physical Properties | | | |
Molecular Weight: 492.558 g/mol | logS: -8.24497 | SlogP: 6.05397 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0927685 | Sterimol/B1: 2.35736 | Sterimol/B2: 4.88101 | Sterimol/B3: 5.2124 |
Sterimol/B4: 10.5921 | Sterimol/L: 19.9589 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 815.168 | Positive charged surface: 527.469 | Negative charged surface: 287.699 | Volume: 465.25 |
Hydrophobic surface: 605.662 | Hydrophilic surface: 209.506 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |