Physical Properties | | | |
Molecular Weight: 434.448 g/mol | logS: -5.85179 | SlogP: 2.76947 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.083483 | Sterimol/B1: 2.61679 | Sterimol/B2: 5.70084 | Sterimol/B3: 6.39763 |
Sterimol/B4: 7.61007 | Sterimol/L: 18.4862 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 731.832 | Positive charged surface: 442.211 | Negative charged surface: 285.897 | Volume: 399 |
Hydrophobic surface: 550.779 | Hydrophilic surface: 181.053 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |