Physical Properties | | | |
Molecular Weight: 386.427 g/mol | logS: -5.43531 | SlogP: 3.9029 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0871229 | Sterimol/B1: 2.75468 | Sterimol/B2: 4.17699 | Sterimol/B3: 4.84927 |
Sterimol/B4: 5.93375 | Sterimol/L: 17.7098 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 649.263 | Positive charged surface: 360.339 | Negative charged surface: 280.566 | Volume: 368.75 |
Hydrophobic surface: 534.807 | Hydrophilic surface: 114.456 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 1 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |