Physical Properties | | | |
Molecular Weight: 468.509 g/mol | logS: -6.73414 | SlogP: 5.02867 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0297827 | Sterimol/B1: 2.09577 | Sterimol/B2: 3.58199 | Sterimol/B3: 3.72501 |
Sterimol/B4: 14.4247 | Sterimol/L: 18.5242 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 788.358 | Positive charged surface: 479.578 | Negative charged surface: 304.49 | Volume: 444.375 |
Hydrophobic surface: 640.632 | Hydrophilic surface: 147.726 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |