Physical Properties | | | |
Molecular Weight: 414.509 g/mol | logS: -7.1939 | SlogP: 4.7097 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.102532 | Sterimol/B1: 2.34645 | Sterimol/B2: 4.27293 | Sterimol/B3: 7.25323 |
Sterimol/B4: 7.35805 | Sterimol/L: 18.7917 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 686.841 | Positive charged surface: 483.079 | Negative charged surface: 200.185 | Volume: 409.75 |
Hydrophobic surface: 567.826 | Hydrophilic surface: 119.015 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |