Physical Properties | | | |
Molecular Weight: 452.531 g/mol | logS: -5.9553 | SlogP: 4.04022 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.109822 | Sterimol/B1: 2.57197 | Sterimol/B2: 4.45591 | Sterimol/B3: 4.77341 |
Sterimol/B4: 11.7134 | Sterimol/L: 18.4575 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 740.873 | Positive charged surface: 441.687 | Negative charged surface: 299.185 | Volume: 420.25 |
Hydrophobic surface: 612.155 | Hydrophilic surface: 128.718 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |