Physical Properties | | | |
Molecular Weight: 427.916 g/mol | logS: -6.82259 | SlogP: 4.0655 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0670563 | Sterimol/B1: 2.27538 | Sterimol/B2: 3.00627 | Sterimol/B3: 5.0226 |
Sterimol/B4: 9.94704 | Sterimol/L: 18.1547 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 673.439 | Positive charged surface: 359.493 | Negative charged surface: 313.946 | Volume: 373.75 |
Hydrophobic surface: 436.381 | Hydrophilic surface: 237.058 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |