Physical Properties | | | |
Molecular Weight: 402.406 g/mol | logS: -4.88745 | SlogP: 2.6774 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0466112 | Sterimol/B1: 2.10185 | Sterimol/B2: 2.56073 | Sterimol/B3: 4.51159 |
Sterimol/B4: 9.11937 | Sterimol/L: 18.4301 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 629.196 | Positive charged surface: 359.989 | Negative charged surface: 269.207 | Volume: 338 |
Hydrophobic surface: 446.889 | Hydrophilic surface: 182.307 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |