Physical Properties | | | |
Molecular Weight: 382.412 g/mol | logS: -6.21463 | SlogP: 4.20942 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0472138 | Sterimol/B1: 2.1888 | Sterimol/B2: 2.38197 | Sterimol/B3: 5.33278 |
Sterimol/B4: 8.6603 | Sterimol/L: 19.3276 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 682.092 | Positive charged surface: 402.602 | Negative charged surface: 279.49 | Volume: 362.625 |
Hydrophobic surface: 542.914 | Hydrophilic surface: 139.178 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |