Physical Properties | | | |
Molecular Weight: 401.26 g/mol | logS: -5.7523 | SlogP: 3.7084 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0782265 | Sterimol/B1: 2.42295 | Sterimol/B2: 3.48996 | Sterimol/B3: 4.47895 |
Sterimol/B4: 8.29993 | Sterimol/L: 16.1726 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 575.074 | Positive charged surface: 283.171 | Negative charged surface: 291.904 | Volume: 334.125 |
Hydrophobic surface: 471.121 | Hydrophilic surface: 103.953 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |