Physical Properties | | | |
Molecular Weight: 336.778 g/mol | logS: -6.43234 | SlogP: 3.4812 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.00858506 | Sterimol/B1: 2.5308 | Sterimol/B2: 2.5927 | Sterimol/B3: 3.55867 |
Sterimol/B4: 4.11534 | Sterimol/L: 19.7 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 554.133 | Positive charged surface: 279.061 | Negative charged surface: 275.072 | Volume: 276.625 |
Hydrophobic surface: 398.812 | Hydrophilic surface: 155.321 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |