Physical Properties | | | |
Molecular Weight: 391.474 g/mol | logS: -6.00349 | SlogP: 5.26842 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.361435 | Sterimol/B1: 2.35711 | Sterimol/B2: 2.47806 | Sterimol/B3: 8.06984 |
Sterimol/B4: 9.90542 | Sterimol/L: 13.8631 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 624.945 | Positive charged surface: 376.202 | Negative charged surface: 244.959 | Volume: 382.75 |
Hydrophobic surface: 529.636 | Hydrophilic surface: 95.309 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 1 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |