Physical Properties | | | |
Molecular Weight: 405.444 g/mol | logS: -7.11501 | SlogP: 4.87959 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0290648 | Sterimol/B1: 2.14713 | Sterimol/B2: 3.41794 | Sterimol/B3: 3.57298 |
Sterimol/B4: 9.27638 | Sterimol/L: 17.9179 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 663.984 | Positive charged surface: 320.008 | Negative charged surface: 343.975 | Volume: 356.125 |
Hydrophobic surface: 442.298 | Hydrophilic surface: 221.686 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |