Physical Properties | | | |
Molecular Weight: 409.489 g/mol | logS: -6.791 | SlogP: 5.19434 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.102138 | Sterimol/B1: 2.07472 | Sterimol/B2: 3.18569 | Sterimol/B3: 4.35566 |
Sterimol/B4: 12.4686 | Sterimol/L: 17.2281 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 722.571 | Positive charged surface: 406.93 | Negative charged surface: 310.769 | Volume: 403.25 |
Hydrophobic surface: 647.714 | Hydrophilic surface: 74.857 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |