Physical Properties | | | |
Molecular Weight: 379.324 g/mol | logS: -6.25742 | SlogP: 4.0087 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0157002 | Sterimol/B1: 3.06039 | Sterimol/B2: 3.49721 | Sterimol/B3: 4.81634 |
Sterimol/B4: 6.01886 | Sterimol/L: 20.1957 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 634.363 | Positive charged surface: 268.842 | Negative charged surface: 365.52 | Volume: 330.875 |
Hydrophobic surface: 423.369 | Hydrophilic surface: 210.994 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |