Physical Properties | | | |
Molecular Weight: 398.422 g/mol | logS: -7.06533 | SlogP: 3.42684 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0986622 | Sterimol/B1: 2.09441 | Sterimol/B2: 3.46349 | Sterimol/B3: 4.52126 |
Sterimol/B4: 10.988 | Sterimol/L: 15.6745 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 655.979 | Positive charged surface: 390.557 | Negative charged surface: 260.207 | Volume: 369.375 |
Hydrophobic surface: 514.729 | Hydrophilic surface: 141.25 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |