Physical Properties | | | |
Molecular Weight: 399.555 g/mol | logS: -5.16461 | SlogP: 3.1637 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.197673 | Sterimol/B1: 2.19225 | Sterimol/B2: 6.27232 | Sterimol/B3: 8.03427 |
Sterimol/B4: 9.72937 | Sterimol/L: 16.795 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 773.908 | Positive charged surface: 534.989 | Negative charged surface: 238.919 | Volume: 427.125 |
Hydrophobic surface: 676.006 | Hydrophilic surface: 97.902 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |