Physical Properties | | | |
Molecular Weight: 408.457 g/mol | logS: -8.54284 | SlogP: 5.853 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0328389 | Sterimol/B1: 2.55744 | Sterimol/B2: 3.95402 | Sterimol/B3: 3.95994 |
Sterimol/B4: 9.0209 | Sterimol/L: 20.4445 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 719.41 | Positive charged surface: 431.479 | Negative charged surface: 276.278 | Volume: 395.25 |
Hydrophobic surface: 635.58 | Hydrophilic surface: 83.83 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |