Physical Properties | | | |
Molecular Weight: 365.143 g/mol | logS: -3.79868 | SlogP: 2.2218 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0012117 | Sterimol/B1: 2.16866 | Sterimol/B2: 2.24754 | Sterimol/B3: 4.59073 |
Sterimol/B4: 5.67819 | Sterimol/L: 17.2259 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 531.14 | Positive charged surface: 253.794 | Negative charged surface: 277.346 | Volume: 272.125 |
Hydrophobic surface: 339.239 | Hydrophilic surface: 191.901 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |