Physical Properties | | | |
Molecular Weight: 421.605 g/mol | logS: -5.51801 | SlogP: 4.4323 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0368916 | Sterimol/B1: 2.72401 | Sterimol/B2: 3.62853 | Sterimol/B3: 3.98246 |
Sterimol/B4: 9.34604 | Sterimol/L: 22.8033 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 797.514 | Positive charged surface: 574.428 | Negative charged surface: 223.086 | Volume: 449.125 |
Hydrophobic surface: 733.496 | Hydrophilic surface: 64.018 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |