Physical Properties | | | |
Molecular Weight: 322.179 g/mol | logS: -2.93707 | SlogP: 1.834 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.174485 | Sterimol/B1: 3.34201 | Sterimol/B2: 3.95074 | Sterimol/B3: 4.61267 |
Sterimol/B4: 5.38287 | Sterimol/L: 12.6242 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 453.153 | Positive charged surface: 211.114 | Negative charged surface: 242.039 | Volume: 236.875 |
Hydrophobic surface: 254.866 | Hydrophilic surface: 198.287 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |