Physical Properties | | | |
Molecular Weight: 402.45 g/mol | logS: -7.74558 | SlogP: 5.13774 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.00656451 | Sterimol/B1: 2.50316 | Sterimol/B2: 2.54807 | Sterimol/B3: 3.19828 |
Sterimol/B4: 6.39059 | Sterimol/L: 25.2693 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 728.367 | Positive charged surface: 460.259 | Negative charged surface: 268.108 | Volume: 387.875 |
Hydrophobic surface: 622.831 | Hydrophilic surface: 105.536 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |