Physical Properties | | | |
Molecular Weight: 457.581 g/mol | logS: -8.01994 | SlogP: 7.20232 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.204991 | Sterimol/B1: 2.05079 | Sterimol/B2: 5.14882 | Sterimol/B3: 5.66006 |
Sterimol/B4: 10.5826 | Sterimol/L: 16.7205 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 746.647 | Positive charged surface: 422.245 | Negative charged surface: 324.402 | Volume: 463.875 |
Hydrophobic surface: 681.124 | Hydrophilic surface: 65.523 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |