Physical Properties | | | |
Molecular Weight: 419.861 g/mol | logS: -5.58078 | SlogP: 3.0138 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.13857 | Sterimol/B1: 2.61708 | Sterimol/B2: 3.09625 | Sterimol/B3: 6.10863 |
Sterimol/B4: 8.87111 | Sterimol/L: 16.2135 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 674.374 | Positive charged surface: 374.759 | Negative charged surface: 299.614 | Volume: 381 |
Hydrophobic surface: 549.458 | Hydrophilic surface: 124.916 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |