Physical Properties | | | |
Molecular Weight: 414.801 g/mol | logS: -5.46995 | SlogP: 2.77822 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0643503 | Sterimol/B1: 2.72646 | Sterimol/B2: 4.19635 | Sterimol/B3: 5.21919 |
Sterimol/B4: 7.60012 | Sterimol/L: 16.6008 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 632.141 | Positive charged surface: 324.375 | Negative charged surface: 307.766 | Volume: 347.375 |
Hydrophobic surface: 416.482 | Hydrophilic surface: 215.659 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |