Physical Properties | | | |
Molecular Weight: 403.183 g/mol | logS: -7.31091 | SlogP: 6.43182 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0546967 | Sterimol/B1: 2.16908 | Sterimol/B2: 3.67071 | Sterimol/B3: 4.69129 |
Sterimol/B4: 6.58421 | Sterimol/L: 17.7184 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 590.412 | Positive charged surface: 216.59 | Negative charged surface: 373.823 | Volume: 314.5 |
Hydrophobic surface: 430.854 | Hydrophilic surface: 159.558 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |